Name | N-carbobenzyloxy-L-serine methyl ester |
Synonyms | Z-Ser-OMe Z-Ser-OMe (Syrup) CBZ-L-Serine methyleester N-CBZ-L-SERINE METHYL ESTER N-Cbz-L-Serine Methyl Ester N-Carbobenzoxy-L-serine methyl ester N-CARBOBENZOXY-L-SERINE METHYL ESTER N-carbobenzyloxy-L-serine methyl ester N-CARBOBENZYLOXY-L-SERINE METHYL ESTER methyl ((benzyloxy)carbonyl)-L-serinate methyl N-[(benzyloxy)carbonyl]-L-serinate L-Serine, N-[(phenylmethoxy)carbonyl]-, methyl ester (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoic acid methyl ester |
CAS | 1676-81-9 |
EINECS | 605-484-2 |
InChI | InChI=1/C12H15NO5/c1-17-11(15)10(7-14)13-12(16)18-8-9-5-3-2-4-6-9/h2-6,10,14H,7-8H2,1H3,(H,13,16)/t10-/m0/s1 |
Molecular Formula | C12H15NO5 |
Molar Mass | 253.25 |
Density | 1.2499 (rough estimate) |
Melting Point | 41-43°C(lit.) |
Boling Point | 170°C0.01mm Hg(lit.) |
Flash Point | >230°F |
Solubility | Chloroform, Methanol |
Vapor Presure | 1.3E-08mmHg at 25°C |
Appearance | Viscous Liquid or Solid |
Color | Pale yellow |
pKa | 10.49±0.46(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | -15 ° (C=1, MeOH) |
MDL | MFCD00077039 |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29242990 |
Preparation | N-benzyloxycarbonyl-L-serine methyl ester is an amino acid derivative, which can be obtained by reacting L-serine methyl ester hydrochloride with benzyl chloroformate. The base can be selected from sodium bicarbonate and sodium carbonate. |
Use | This protective serine has been used as a Cbz analog of Garner aldehyde, 1,22, 3-diaminopropanol and 2-amino -1, 3-propanediol The raw material of optically active derivatives. |